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Article

The role of the Agouti-Related Protein in energy balance regulation.

Cellular and molecular life sciences : CMLS - 1 Sept 2008

Ilnytska O, Argyropoulos G

Abstract excerpt

The Agouti-Related Protein (AgRP) is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally. AgRP-deficiency, on the other hand, leads to increased metabolic rate and a longer lifespan when mice consume a high fat diet. In humans, AgRP polymorphisms have been consistently associated with resistance to fatness in Blacks and Whites and resistance to...

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Identifiers

PMID: 18470724
DOI: 10.1007/s00018-008-8104-4
PMCID: PMC2748318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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