Article

Treslin and its role in the assembly of the replicative DNA helicase

2020-01-01

Abstract excerpt

DNA replication is an essential biochemical process that underlies genetic inheritance. In eukaryotic cells, this process is carried out by a multi-subunit protein complex called replisome. The core of replisome is made up of six-subunit protein ring Mcm2–7, which contains weak DNA helicase activity. In order to fully activate the helicase activity, protein co-activators of Cdc45 and GINS have to be recruited to a...

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Literature Corpus work: 5a8c8636-e914-54b8-bb39-4468e0d77659
DOI: 10.17863/cam.48462

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