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Article

Drosophila Sld5 is essential for normal cell cycle progression and maintenance of genomic integrity.

Biochemical and biophysical research communications - 10 Sept 2010

Gouge Catherine A, Christensen Tim W

Abstract excerpt

Essential for the normal functioning of a cell is the maintenance of genomic integrity. Failure in this process is often catastrophic for the organism, leading to cell death or mis-proliferation. Central to genomic integrity is the faithful replication of DNA during S phase. The GINS complex has recently come to light as a critical player in DNA replication through stabilization of MCM2-7 and Cdc45 as a member of...

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Identifiers

PMID: 20709026
DOI: 10.1016/j.bbrc.2010.08.033
PMCID: PMC2939264

Genes

MCM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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