Article
Characterising replisome disassembly in human cells
2022-07-12
Abstract excerpt
To ensure faultless duplication of the entire genome, eukaryotic replication initiates from thousands of replication origins. Replication forks emanating from origins move through the chromatin until they encounter forks from neighbouring origins, at which point they terminate. In the final stages of this process the replication machinery (replisome) is unloaded from chromatin and disassembled. Work from model org...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- ac43950a-bde5-5eeb-ace3-0964ae9606dc
- DOI
- 10.1101/2022.07.12.499744