Back to search

Article

Regional genetic correlations highlight relationships between neurodegenerative diseases and the immune system

2022-12-07

Abstract excerpt

Neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), Lewy body dementia (LBD) and amyotrophic lateral sclerosis (ALS), are devastating complex diseases that result in a physical and psychological burden to patients and their families. There have been significant efforts to understand the genetic basis of neurodegenerative diseases resulting in the identification of disease risk...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
59264b1d-3287-5d07-8482-b0eb722bd222
DOI
10.1101/2022.12.07.22283179
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Regional genetic correlations highlight relationships between neurodegenerative diseases and the immune systemDOI 10.1101/2022.12.07.22283179
Regional genetic correlations highlight relationships between neurodegenerative disease loci and the immune system.Semantic proximity
Genetic overlap between Alzheimer's disease and immune-mediated diseases: An atlas of shared genetic determinants and biological convergenceSemantic proximity
Genetic overlap between Alzheimer's disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence.Semantic proximity
Genomic partitioning of Alzheimer’s disease in humans reveals non-CNS etiologySemantic proximity
Local genetic correlations exist among neurodegenerative and neuropsychiatric diseasesSemantic proximity
Immune-related genetic enrichment in frontotemporal dementiaSemantic proximity
Cell-type-specific genetic architecture reveals neuronal and immune contributions to neuropsychiatric disorders.Semantic proximity
Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human geneticsSemantic proximity
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.Semantic proximity
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.Semantic proximity
Population and single-cell analyses reveal immune cell-specific expression profiles associated with Alzheimer's disease risk.Semantic proximity
Deciphering the peripheral immune landscape of Alzheimer's disease through integrated multi-omics research and cohort validation.Semantic proximity
Select a neighboring publication to make it the new centre.