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Genetic overlap between Alzheimer's disease and immune-mediated diseases: An atlas of shared genetic determinants and biological convergence

2023-09-28

Abstract excerpt

<title>Abstract</title><p>The occurrence of immune disease comorbidities in Alzheimer’s disease (AD) has been observed in both epidemiological and molecular studies, suggesting a neuroinflammatory basis in AD. However, their shared genetic components have not been systematically studied. Here, we composed an atlas of the shared genetic associations between 11 immune-mediated diseases and AD by analyzing genome-wid...

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Literature Corpus work: 5da5eddd-e5f8-533e-a3a3-5fbe9c2052ad
DOI: 10.21203/rs.3.rs-3346282/v1

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