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Article

Regional genetic correlations highlight relationships between neurodegenerative disease loci and the immune system.

Communications biology - 15 Jul 2023

Lona-Durazo Frida, Reynolds Regina H, Scholz Sonja W, Ryten Mina, Gagliano Taliun Sarah A

Abstract excerpt

Neurodegenerative diseases, including Alzheimer's and Parkinson's disease, are devastating complex diseases resulting in physical and psychological burdens on patients and their families. There have been important efforts to understand their genetic basis leading to the identification of disease risk-associated loci involved in several molecular mechanisms, including immune-related pathways. Regional, in contrast...

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Identifiers

PMID: 37454237
DOI: 10.1038/s42003-023-05113-5
PMCID: PMC10349864

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