Article

Crowding on DNA modulates SSB protein binding mode kinetics

2026-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Single-stranded DNA-binding (SSB) proteins play a crucial role in DNA replication by binding to single-stranded DNA (ssDNA) in multiple binding modes, depending on conditions such as salt and protein concentrations. The coverage-dependent effects on the kinetics of these binding modes remain incompletely understood. In particular, the bimodal binding kinetics and the further SSB-ssDNA shortening...

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Literature Corpus work: 57be394d-b82e-5132-b482-1553c2d3e69a
DOI: 10.64898/2026.07.02.736164

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