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Hollow condensates emerge from gelation-induced spinodal decomposition

2025-06-27

Abstract excerpt

Recent studies have identified diverse hollow biomolecular condensates, characterized by biomolecule-depleted interiors surrounded by biomolecule-rich shells. Although several formation mechanisms have been proposed, a general thermodynamic driving force remains elusive. Here, we investigate a well-defined system in which the human transcription factor p53 and non-specific double-stranded DNA (dsDNA) form biomolec...

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Literature Corpus work
26788eba-95b0-5c74-b57e-4bcdb792836e
DOI
10.1101/2025.06.25.661497
Open publication

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Hollow condensates emerge from gelation-induced spinodal decompositionDOI 10.1101/2025.06.25.661497
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