Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generating CRISPR Alleles in Drosophila.

Cold Spring Harbor protocols - 2 May 2024

Gratz Scott, O'Connor-Giles Kate M, Wildonger Jill

Abstract excerpt

CRISPR gene editing is a versatile and efficient approach for generating a wide variety of genetic reagents in flies. This unparalleled ability to manipulate the genome has revolutionized neuroscience, allowing Drosophila neurobiologists to readily generate new alleles to probe gene function, investigate the functional consequences of disease-associated variants, tag endogenous proteins to follow their dynamic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Clustered Regularly Interspaced Short Palindromic Repeats
Share to CRISPR-Cas Systems

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila

Share to Gene Editing

Source

Identifiers

PMID: 37788869
DOI: 10.1101/pdb.prot108256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generating CRISPR Alleles in Drosophila.PMID 37788869Read ↗

Systematic Evaluation of Drosophila CRISPR Tools Reveals Safe and Robust Alternatives to Autonomous Gene Drives in Basic Research.Semantic proximity Read ↗

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila.Semantic proximity Read ↗

Upgraded CRISPR/Cas9 Tools for Tissue-Specific Mutagenesis in <i>Drosophila</i>Semantic proximity Read ↗

Tools and strategies for scarless allele replacement in Drosophila using CRISPR/Cas9.Semantic proximity Read ↗

An optimized CRISPR/Cas toolbox for efficient germline and somatic genome engineering in <i>Drosophila</i>Semantic proximity Read ↗

A large-scale resource for tissue-specific CRISPR mutagenesis in <i>Drosophila</i>Semantic proximity Read ↗

Genome editing. The mutagenic chain reaction: a method for converting heterozygous to homozygous mutations.Semantic proximity Read ↗

Large-scale transgenic <i>Drosophila</i> resource collections for loss- and gain-of-function studiesSemantic proximity Read ↗

Optimized strategy for in vivo Cas9-activation in Drosophila.Semantic proximity Read ↗

A streamlined CRISPR pipeline to reliably generate zebrafish frameshifting alleles.Semantic proximity Read ↗

DIPA-CRISPR Gene Editing: A Review Exploring New Horizons in Disease ManagementSemantic proximity Read ↗

Highly efficient CRISPR/Cas9-mediated tissue specific mutagenesis in <i>Drosophila</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.