Article

Upgraded CRISPR/Cas9 Tools for Tissue-Specific Mutagenesis in <i>Drosophila</i>

2020-07-03

Abstract excerpt

<h4>ABSTRACT</h4> CRISPR/Cas9 has emerged as a powerful technology for tissue-specific mutagenesis. However, tissue-specific CRISPR/Cas9 tools currently available in Drosophila remain deficient in three significant ways. First, many existing gRNAs are inefficient, such that further improvements of gRNA expression constructs are needed for more efficient and predictable mutagenesis in both somatic and germline ti...

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Literature Corpus work: 0731b575-178e-5eb2-b24c-cb507dbc58a5
DOI: 10.1101/2020.07.02.185652

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