Article

A mouse model for functional dissection of TAB1 O-GlcNAcylation

2020-06-16

Abstract excerpt

<h4>Background: </h4> O-GlcNAcylation is a posttranslational modification associated with various physiological and pathophysiological processes including diabetes, cancer, neurodegeneration and inflammation. However, the biological mechanisms underlying the role of specific O-GlcNAc sites and their link to phenotypes remain largely unexplored due to lack of suitable in vivo models. TGF-β activated kinase-1 bindi...

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Literature Corpus work: 55e4d2fb-22a2-555b-ab32-ce9b2e306dbb
DOI: 10.12688/wellcomeopenres.15394.2

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