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Article

Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1.

FEBS letters - 2 Jun 2000

Sakurai H, Miyoshi H, Mizukami J, Sugita T

Abstract excerpt

TAK1 is a mitogen-activated protein kinase kinase kinase (MAP3K) that is involved in the c-Jun N-terminal kinase/p38 MAPKs and NF-kappaB signaling pathways. Here, we characterized the molecular mechanisms of TAK1 activation by its specific activator TAB1. Autophosphorylation of two threonine resi...

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Source

Identifiers

PMID: 10838074
DOI: 10.1016/s0014-5793(00)01588-x

Genes

TAB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10838074-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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