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The effects of post-translational modifications on Th17/Treg cell differentiation

1 Feb 2022

Abstract excerpt

T cells which play an essential role in immune homeostasis and infection. Dysregulation of the Th17/Treg cell balance was shown to be implicated in the development and progression of several disorders such as autoimmune disease, inflammatory disease, and cancer. Multiple factors, including T cell receptor (TCR) signals, cytokines, metabolic and epigenetic regulators can influence the differentiation of Th17 and...

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PMID: 35120998
DOI: 10.1016/j.bbamcr.2022.119223

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