Article

Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia

2019-11-22

Abstract excerpt

<h4>INTRODUCTION</h4> The presymptomatic phase of neurodegenerative disease can last many years, with sustained cognitive function despite progressive atrophy. We investigate this phenomenon in familial Frontotemporal dementia (FTD). <h4>METHODS</h4> We studied 121 presymptomatic FTD mutation carriers and 134 family members without mutations, using multivariate data-driven approach to link cognitive performance wi...

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Literature Corpus work: 556a3dc3-d6fc-58a8-82a2-634f80b56070
DOI: 10.1101/19012203

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