Article

Cellular signatures of functional resilience in presymptomatic frontotemporal dementia

2025-02-25

Abstract excerpt

Frontotemporal dementia (FTD) shows autosomal dominant transmission in up to a third of families, enabling the study of presymptomatic and prodromal phases. Despite self-reported well-being and normal daily cognitive functioning, brain structural changes are evident a decade or more before the expected onset of disease. This divergence between cognitive function and brain structure contrasts with the coupling of s...

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Identifiers and source

Literature Corpus work: 50f14250-7cf2-5606-97be-fe0701255544
DOI: 10.1101/2025.02.24.25322778

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