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Article

Preferential degradation of cognitive networks differentiates Alzheimer’s disease from ageing

15 Feb 2018

Abstract excerpt

Converging evidence from structural, metabolic and functional connectivity MRI suggests that neurodegenerative diseases, such as Alzheimer's disease, target specific neural networks. However, age-related network changes commonly co-occur with neuropathological cascades, limiting efforts to disentangle disease-specific alterations in network function from those associated with normal ageing. Here we elucidate the...

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PMID: 29522171
DOI: 10.1093/brain/awy053

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