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Article

Harnessing CRISPR-Cas systems for bacterial genome editing.

Trends in microbiology - 1 Apr 2015

Selle Kurt, Barrangou Rodolphe

Abstract excerpt

Manipulation of genomic sequences facilitates the identification and characterization of key genetic determinants in the investigation of biological processes. Genome editing via clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated (Cas) constitutes a next-generation method for programmable and high-throughput functional genomics. CRISPR-Cas systems are readily reprogrammed to...

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PMID: 25698413
DOI: 10.1016/j.tim.2015.01.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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