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Article

Mobile-CRISPRi: Enabling Genetic Analysis of Diverse Bacteria

2018-05-05

Abstract excerpt

<h4>Introductory paragraph</h4> The vast majority of bacteria, including human pathogens and microbiome species, lack genetic tools needed to systematically associate genes with phenotypes. This is the major impediment to understanding the fundamental contributions of genes and gene networks to bacterial physiology and human health. CRISPRi, a versatile method of blocking gene expression using a catalytically ina...

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Literature Corpus work
d030321f-3e12-5059-b2c7-6c398c28ea22
DOI
10.1101/315499
Open publication

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