Article

Lamin B1-dependent regulation of human separase in mitosis

2024-11-28

Abstract excerpt

<h4>ABSTRACT</h4> Separase plays a central role in chromosome separation during mitosis and in centrosome cycle. Tight control of separase activity is required to prevent unscheduled resolution of sister chromatid cohesion and centrosome aberrations, thereby preserving genome stability. In mammals, despite their disassembly in early mitosis, some nuclear envelope components possess mitotic roles, but links with s...

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Literature Corpus work: 53523419-f867-5135-81a5-89ba4e467564
DOI: 10.1101/2024.11.28.625860

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