Back to search

Article

Transcription factor Sp1 regulates mitotic fidelity through Aurora B kinase-mediated condensin I localization

2020-06-20

Abstract excerpt

Mitotic chromosome assembly is essential for faithful chromosome segregation. Despite their salient role directing interphase chromatin organization, little is known about how transcription factors mediate this process during mitosis. Here, we characterize a mitosis-specific role for transcription factor specificity protein 1 (Sp1). Sp1 localizes to mitotic centromeres and auxin-induced rapid Sp1 degradation resul...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a36f953e-e4f9-5a1b-a27a-169ff40731ab
DOI
10.1101/2020.06.19.158030
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transcription factor Sp1 regulates mitotic fidelity through Aurora B kinase-mediated condensin I localizationDOI 10.1101/2020.06.19.158030
Select a neighboring publication to make it the new centre.