Article
Transcription factor Sp1 regulates mitotic fidelity through Aurora B kinase-mediated condensin I localization
2020-06-20
Abstract excerpt
Mitotic chromosome assembly is essential for faithful chromosome segregation. Despite their salient role directing interphase chromatin organization, little is known about how transcription factors mediate this process during mitosis. Here, we characterize a mitosis-specific role for transcription factor specificity protein 1 (Sp1). Sp1 localizes to mitotic centromeres and auxin-induced rapid Sp1 degradation resul...
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Identifiers and source
- Literature Corpus work
- a36f953e-e4f9-5a1b-a27a-169ff40731ab
- DOI
- 10.1101/2020.06.19.158030
