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Article

Epithelial re-organization and dynamics of progression through mitosis in Drosophila separase complex mutants.

Journal of cell science - 15 Feb 2005

Pandey Rahul, Heidmann Stefan, Lehner Christian F

Abstract excerpt

Separase cleaves a subunit of the cohesin complex and thereby promotes sister chromatid separation during mitotic and meiotic divisions. Drosophila separase associates with regulatory subunits encoded by the pimples and three rows genes. Three rows and Pimples, the Drosophila securin, are required for sister chromatid separation during mitosis. Budding yeast separase provides other functions in addition to...

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Source

Identifiers

PMID: 15671062
DOI: 10.1242/jcs.01663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Epithelial re-organization and dynamics of progression through mitosis in Drosophila separase complex mutants.PMID 15671062Read ↗

Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition.Semantic proximity Read ↗

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The radially swollen 4 separase mutation of Arabidopsis thaliana blocks chromosome disjunction and disrupts the radial microtubule system in meiocytes.Semantic proximity Read ↗

Cohesin cleavage by separase required for anaphase and cytokinesis in human cells.Semantic proximity Read ↗

Genetic interactions between Cdk1-CyclinB and the Separase complex in Drosophila.Semantic proximity Read ↗

Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans.Semantic proximity Read ↗

Elucidation of novel budding yeast separase mutants.Semantic proximity Read ↗

Drosophila securin destruction involves a D-box and a KEN-box and promotes anaphase in parallel with Cyclin A degradation.Semantic proximity Read ↗

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