Article
Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase.
Genes & development - 1 Nov 1998
Furuya K, Takahashi K, Yanagida M
Abstract excerpt
The loss of sister chromatid cohesion triggers anaphase spindle movement. The budding yeast Mcd1/Scc1 protein, called cohesin, is required for associating chromatids, and proteins homologous to it exist in a variety of eukaryotes. Mcd1/Scc1 is removed from chromosomes in anaphase and degrades in...
Topics
- Anaphase
- Cell Cycle Proteins
- Chromatids
- Chromosomal Proteins, Non-Histone
- Conserved Sequence
- DNA Ligases
- Fungal Proteins
- G1 Phase
- Genes, Essential
- Humans
- Metaphase
- Mutation
- Nuclear Proteins
- Phosphoproteins
- S Phase
- Saccharomyces cerevisiae Proteins
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins