Article

The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

2020-11-17

Abstract excerpt

<h4>SUMMARY</h4> The spindle assembly checkpoint (SAC) is an evolutionarily conserved safety mechanism that maintains genomic stability. However, despite the understanding of the fundamental mechanisms that control the SAC, it remains unknown how signaling pathways directly interact with and regulate the mitotic checkpoint activity. In response to extracellular stimuli, a diverse network of signaling pathways inv...

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Literature Corpus work: 07b7ab98-08d0-5860-936b-78cc2395ab58
DOI: 10.1101/2020.11.17.386177

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