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Article

PEG-fDAO Reduces Lung Inflammation in Chronic Granulomatous Disease Mice Post Challenge with Nonviable Candida Albicans

2021-03-09

Abstract excerpt

<title>Abstract</title> <p>We previously reported that polyethylene glycol-conjugated recombinant porcine D-amino acid oxidase (PEG-pDAO) could supply reactive oxygen species (ROS) to defective NADPH oxidase in neutrophils of patients with chronic granulomatous disease (CGD), and neutrophils regain bactericidal activity <italic>in vitro</italic>. In the present study, we employed an <italic>in vivo</italic> nonvi...

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Literature Corpus work
530e88c2-164d-55b3-aae3-104603033151
DOI
10.21203/rs.3.rs-216646/v1
Open publication

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PEG-fDAO Reduces Lung Inflammation in Chronic Granulomatous Disease Mice Post Challenge with&nbsp;Nonviable Candida AlbicansDOI 10.21203/rs.3.rs-216646/v1
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