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Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation to Protect against Bacterial Infections

2018-11-15

Abstract excerpt

<h4>ABSTRACT</h4> Pneumonia remains a global health threat, in part due to expanding categories of susceptible individuals and increasing prevalence of antibiotic resistant pathogens. However, therapeutic stimulation of the lungs’ mucosal defenses by inhaled exposure to a synergistic combination of Toll-like receptor (TLR) agonists known as Pam2-ODN promotes mouse survival of pneumonia caused by a wide array of p...

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Literature Corpus work
0eb9b45e-7444-5cf1-b1a7-d3003c257dd5
DOI
10.1101/471649
Open publication

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Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation to Protect against Bacterial InfectionsDOI 10.1101/471649
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