Article

PEG-fDAO Reduces Lung Inflammation in Chronic Granulomatous Disease Mice Post Challenge With Nonviable Candida Albicans

2021-08-20

Abstract excerpt

<title>Abstract</title> We previously reported that polyethylene glycol-conjugated recombinant porcine D-amino acid oxidase (PEG-pDAO) could supply reactive oxygen species (ROS) to defective NADPH oxidase in neutrophils of patients with chronic granulomatous disease (CGD), and neutrophils regain bactericidal activity <italic>in vitro</italic>. In the present study, we employed an <italic>in vivo </italic>nonvi...

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Literature Corpus work: 4180a408-1dc2-5112-a015-c0fbb9e395f8
DOI: 10.21203/rs.3.rs-805346/v1

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