Article

Contribution of epigenetic changes to escape from X-chromosome inactivation

2021-03-03

Abstract excerpt

<h4>Background</h4> X-chromosome inactivation (XCI) is the epigenetic inactivation of one of two X chromosomes in XX eutherian mammals. The facultatively heterochromatic inactive X chromosome acquires many chromatin changes including DNA methylation and histone modifications. Despite these changes, some genes escape or variably escape from inactivation, and to the extent that they have been studied, epigenetic ma...

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Literature Corpus work: 4f184a4c-83e9-5904-8351-ead70a0b35b8
DOI: 10.1101/2021.03.03.433635

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