Article

Human Genes Escaping X-inactivation Revealed by Single Cell Expression Data

2018-12-11

Abstract excerpt

<h4>Background</h4> In mammals, sex chromosomes pose an inherent imbalance of gene expression between sexes. In each female somatic cell, random inactivation of one of the X-chromosomes restores this balance. While most genes from the inactivated X-chromosome are silenced, 15-25% are known to escape X-inactivation (termed escapees). The expression levels of these genes are attributed to sex-dependent phenotypic v...

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Literature Corpus work: b1cbe097-9e21-5e53-8b1e-8a42b5866a60
DOI: 10.1101/486084

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