Article

Clonal haematopoiesis without identified genetic drivers: insights from analyses of 407,512 individuals

2026-05-20

Abstract excerpt

Clonal haematopoiesis (CH) becomes ubiquitous as humans age. The role of somatic driver mutations in its development has been studied widely, but little is known about CH without identified genetic drivers, also known as “CH with unknown drivers” (CH-UD). A fundamental unresolved question is whether CH-UD is driven by undiscovered somatic genetic drivers or by other cell-heritable traits. Here, to investigate this...

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Literature Corpus work: 4e09588f-4287-5fef-947c-26148c8aa143
DOI: 10.64898/2026.05.17.26353391

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