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Impact of clonal hematopoiesis on cardiovascular outcomes in cancer patients of the UK Biobank

1 Aug 2025

Abstract excerpt

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alterations (mCAs) have been linked to increased risks of cardiovascular disease (CVD) and mortality. CHIP and mCAs may also then contribute to CVD in cancer patients. Our objective was to investigate the prevalence of CHIP mutations and mCAs in cancer patients, their co-occurrence, and the associated CVD outcomes across...

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PMID: 40779931
DOI: 10.1016/j.esmoop.2025.105539

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