Article

Nucleotide sequence and DNaseI sensitivity are predictive of 3D chromatin architecture

2017-01-27

Abstract excerpt

Recently, Hi-C has been used to probe the 3D chromatin architecture of multiple organisms and cell types. The resulting collections of pairwise contacts across the genome have connected chromatin architecture to many cellular phenomena, including replication timing and gene regulation. However, high resolution (10 kb or finer) contact maps remain scarce due to the expense and time required for collection. A comput...

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Literature Corpus work: 93ec2cdf-00b2-5ad6-8fe8-e0b3e6bf032f
DOI: 10.1101/103614

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