Article

Connecting high-resolution 3D chromatin organization with epigenomics

2020-10-14

Abstract excerpt

The resolution of chromatin conformation capture technologies keeps increasing, and the recent nucleosome resolution chromatin contact maps allow us to explore how fine-scale 3D chromatin organization is related to epigenomic states in human cells. Using publicly available Micro-C datasets, we have developed a deep learning model, CAESAR, to learn a mapping function from epigenomic features to 3D chromatin organiz...

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Literature Corpus work: 14cd230b-d958-5753-bca8-6825f62915ed
DOI: 10.1101/2020.10.13.338004

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