Article

DeepTACT: predicting high-resolution chromatin contacts via bootstrapping deep learning

2018-06-22

Abstract excerpt

High-resolution interactions among regulatory elements are of crucial importance for the understanding of transcriptional regulation and the interpretation of disease mechanism. Hi-C technique allows the genome-wide detection of chromatin contacts. However, unless extremely deep sequencing is performed on a very large number of input cells, current Hi-C experiments do not have high enough resolution to resolve con...

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Literature Corpus work: 129e07f4-f8ac-5bf9-b639-63ca24f51466
DOI: 10.1101/353284

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