Article

Predicting 3D Chromatin Interactions Using Transformer-Enhanced Deep Learning Models

2025-04-16

Abstract excerpt

The three-dimensional (3D) structure of the human genome is essential for regulating gene expression and cellular functions. Chromatin interactions bring distant genomic regions into physical contact, enabling processes like gene regulation, DNA replication, and repair. Disruptions in this organization can lead to diseases such as cancer and genetic disorders. In this study, we propose a Transformer-based deep lea...

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Literature Corpus work: b72a04d8-ef1c-5895-8a51-4ba32fa213d3
DOI: 10.1101/2025.04.10.647995

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