Article

Modelling homing suppression gene drive in haplodiploid organisms

2021-10-13

Abstract excerpt

Gene drives have shown great promise for suppression of pest populations. These engineered alleles can function by a variety of mechanisms, but the most common is the CRISPR homing drive, which converts wild-type alleles to drive alleles in the germline of heterozygotes. Some potential target species are haplodiploid, in which males develop from unfertilized eggs and thus have only one copy of each chromosome. Thi...

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Literature Corpus work: 4c19d610-6121-50f8-82d5-d6ccbe2caaf5
DOI: 10.1101/2021.10.12.464047

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