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Conditional silencing of H-2D <sup>b</sup> class I molecule expression on dendritic cells modulates the protective and pathogenic kinetics of virus-antigen specific CD8 T cell responses during Theiler’s Virus infection

2019-05-09

Abstract excerpt

<h4>ABSTRACT</h4> Theiler’s murine encephalomyelitis virus (TMEV) infection of the central nervous system is rapidly cleared in C57BL/6 mice by an anti-viral CD8 T cell response restricted by the MHC class I molecule, H-2D b . While the CD8 T cell response against neurotropic viruses is well characterized, the identity and function of the antigen presenting cell(s) involved in this process is(are) less well defi...

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Literature Corpus work
4c101032-071f-5de0-853c-e18d63f029a6
DOI
10.1101/632265
Open publication

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Conditional silencing of H-2D <sup>b</sup> class I molecule expression on dendritic cells modulates the protective and pathogenic kinetics of virus-antigen specific CD8 T cell responses during Theiler’s Virus infectionDOI 10.1101/632265
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