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Article

Infiltrating regulatory B cells control neuroinflammation following viral brain infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2014

Mutnal Manohar B, Hu Shuxian, Schachtele Scott J, Lokensgard James R

Abstract excerpt

Previous studies have demonstrated the existence of a subset of B lymphocytes, regulatory B cells (Bregs), which modulate immune function. In this study, in vivo and in vitro experiments were undertaken to elucidate the role of these Bregs in controlling neuroinflammation following viral brain infection. We used multicolor flow cytometry to phenotype lymphocyte subpopulations infiltrating the brain, along with in...

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Identifiers

PMID: 25385825
DOI: 10.4049/jimmunol.1400654
PMCID: PMC4258482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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