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Antigen-specific CD8 T cells are generated and reactivated in the bone marrow following viral brain infections and impact the bone marrow niche

2025-12-26

Abstract excerpt

Bone marrow is the primary immune organ responsible for stem cell maintenance and hematopoiesis. However, the contribution of the bone marrow niche for the generation of adaptive immune responses is less well-understood. We therefore assessed the capacity of virus antigen-specific CD8 T cells to be generated and expanded in bone marrow following acute neurotropic virus infection. Intracranial infection with the ne...

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Literature Corpus work
7c88aa6e-b81d-5823-82fe-a86a03c544b5
DOI
10.64898/2025.12.25.696510
Open publication

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Antigen-specific CD8 T cells are generated and reactivated in the bone marrow following viral brain infections and impact the bone marrow nicheDOI 10.64898/2025.12.25.696510
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