Article

Type 1 and type 2 dendritic cell subsets cooperate to maintain intestinal immune tolerance via integrin αvβ8-mediated TGF-β activation

2026-02-28

Abstract excerpt

<h4>ABSTRACT</h4> The gastrointestinal tract is a unique immunological environment where the host must balance tolerance to commensal microbes with defense against pathogens. A critical mechanism for maintaining this balance is the peripheral conversion of naïve T cells into regulatory T cells (pTregs), a process that depends on the TGF-β cytokine, which is produced in a latent form and must be activated. While t...

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Literature Corpus work: 4c9f2d2b-17fd-57ae-990c-d324049b4787
DOI: 10.64898/2026.02.26.707908

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