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Combining cell type-specific genomic/epigenomic analyses and experimental validation identifies genetic drivers across three neurodegenerative diseases

2026-03-03

Abstract excerpt

<title>Abstract</title> <p> The genetic underpinnings of neurodegenerative disease risk remain poorly characterized due to the lack of a unified framework for synthesizing causal evidence from diverse statistical and biological sources. Here, we present an integrative approach to analyze Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) risk that unifies evidence from Me...

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Literature Corpus work
4bdf6bec-9438-5289-abd7-b407b816667e
DOI
10.21203/rs.3.rs-8779983/v1
Open publication

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Combining cell type-specific genomic/epigenomic analyses and experimental validation identifies genetic drivers across three neurodegenerative diseasesDOI 10.21203/rs.3.rs-8779983/v1
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