Article

Single-cell epigenomic identification of inherited risk loci in Alzheimer’s and Parkinson’s disease

2020-01-06

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWAS) have identified thousands of variants associated with disease phenotypes. However, the majority of these variants do not alter coding sequences, making it difficult to assign their function. To this end, we present a multi-omic epigenetic atlas of the adult human brain through profiling of the chromatin accessibility landscapes and three-dimensional chromat...

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Literature Corpus work: 4a870341-aeda-5e76-bdf3-b2cd1c302a2d
DOI: 10.1101/2020.01.06.896159

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