Article

Increased recombinant AAV production by HEK293 cells using small molecule chemical additives

2022-08-14

Abstract excerpt

Recombinant adeno-associated virus (rAAV) has established itself as a highly efficacious gene delivery vector with a well characterised safety profile allowing broad clinical application. Recent successes in rAAV-mediated gene therapy clinical trials will continue to drive demand for improved rAAV production processes to reduce costs. Here we demonstrate that small molecule bioactive chemical additives can signifi...

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Identifiers and source

Literature Corpus work: 4bc429ef-f94f-5030-85a9-ec4ea1af8fb5
DOI: 10.22541/au.166051625.50657820/v1

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