Article

Diverse Microbial Exposure Enhances CD8 <sup>+</sup> T Cell Effector Memory Output and Function

2026-02-04

Abstract excerpt

Mice with normalized microbial exposure (NME) harbor an immune system that more accurately reflects that of humans compared to mice maintained as specific pathogen-free (SPF). An explanation for the observed alterations in the composition of the T cell compartment in NME mice has not been reported. We compared the T cell landscape in NME versus SPF mice at baseline and after acute LCMV infection. Using the immgenT...

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Literature Corpus work: 4abe9395-1dca-5eef-980d-a9f211ebae43
DOI: 10.64898/2026.02.02.703037

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