Article

Bystander memory-phenotype conventional CD4 <sup>+</sup> T cells exacerbating autoimmune neuroinflammation

2022-06-17

Abstract excerpt

Memory-phenotype (MP) CD4 + T cells are a substantial population of conventional T cells that exist in steady-state mice, and their immunologic functions in autoimmune disease have not yet been studied. In this work, we unveil a unique phenotype of MP CD4 + T cells by analyzing single-cell transcriptomics and T cell receptor (TCR) repertoires. We found that steady-state MP CD4 + T cells exist regardless of germ...

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Literature Corpus work: d6a9cfaa-5937-5b50-b3b7-61af326f7050
DOI: 10.1101/2022.06.17.496529

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