Article

Steady-state memory-phenotype conventional CD4+ T cells exacerbating autoimmune neuroinflammation in bystander manner via Bhlhe40/GM-CSF axis

2022-11-11

Abstract excerpt

<title>Abstract</title> Memory-phenotype (MP) CD4+ T cells are a substantial population of conventional T cells that exist in steady-state mice, and their immunologic functions in autoimmune disease have not yet been studied. In this work, we unveil a unique phenotype of MP CD4+ T cells by analyzing single-cell transcriptomics and T cell receptor (TCR) repertoires. We found that steady-st...

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Literature Corpus work: b587dc21-fc6f-5013-b4e4-f3f91472a32e
DOI: 10.21203/rs.3.rs-2219047/v1

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