Article

An increase in peroxiredoxin 6 expression induces neurotoxic A1 astrocytes in the lumbar spinal cord of amyotrophic lateral sclerosis mice model

2023-01-30

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease with selective degeneration of motor neurons. It has been reported that an increase in the levels of inflammatory cytokines and glial cells such as reactive astrocytes is closely involved in the pathological progression of ALS. Recently, the levels of neuropathic cytotoxic (A1) astrocytes among reactive astrocytes have reportedly increased i...

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Literature Corpus work: 4aa53544-0cb1-518e-b494-9ea507c8785f
DOI: 10.21203/rs.3.rs-2513131/v1

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