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Article

FABP7 upregulation induces a neurotoxic phenotype in astrocytes.

Glia - 1 Dec 2020

Killoy Kelby M, Harlan Benjamin A, Pehar Mariana, Vargas Marcelo R

Abstract excerpt

Fatty acid binding proteins (FABPs) are key regulators of lipid metabolism, energy homeostasis, and inflammation. They participate in fatty acid metabolism by regulating their uptake, transport, and availability of ligands to nuclear receptors. In the adult brain, FABP7 is especially abundant in astrocytes that are rich in cytoplasmic granules originated from damaged mitochondria. Mitochondrial dysfunction and...

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Identifiers

PMID: 32619303
DOI: 10.1002/glia.23879
PMCID: PMC7573932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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