Article

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

2021-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson’s disease (PD) is a progressive neurodegenerative disorder for which there is no successful prevention or intervention. The pathological hallmark for PD involves the self-assembly of functional Alpha-Synuclein (αS) into non-functional amyloid structures. One of the potential therapeutic interventions against PD is the effective inhibition of αS aggregation. However, the bottleneck towa...

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Literature Corpus work: 4a7cf649-dc64-5c23-9122-cad6910ed82f
DOI: 10.1101/2021.05.08.443146

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