Article

Genome-scale Capture C promoter interaction analysis implicates novel effector genes at GWAS loci for bone mineral density

2018-08-31

Abstract excerpt

<h4>ASBTRACT</h4> Osteoporosis is a devastating disease with an essential genetic component. Genome wide association studies (GWAS) have discovered genetic variants robustly associated with bone mineral density (BMD), however they only report genomic signals and not necessarily the precise localization of culprit effector genes. Therefore, we sought to carry out physical and direct ‘variant to gene mapping’ in a...

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Literature Corpus work: 49ba96d5-a4c4-5714-b6e0-dd047c828db0
DOI: 10.1101/405142

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